Related Experiment Video
Updated: Jan 22, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
[Idiopathic Diffuse Pulmonary Ossification Diagnosed by Lung Biopsy]
Shinji Hirai1, Tatsuya Katayama, Satoshi Inoue
1Department of Thoracic Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan.
Abstract:
A case of a 64-year-old woman who had undergone resection of a femoral giant cell tumor in another hospital 35 years before was referred to our hospital for diabetes education. Chest radiography and computed tomography (CT) revealed diffuse densely calcified nodular lesions that appear to be in both lung fields. Since pulmonary metastases of the giant cell tumor of the bone was suspected, she underwent a lung biopsy, which showed diffuse pulmonary ossification (DPO) of the dendriform type. It is extremely rare that idiopathic DPO is diagnosed by lung biopsy.
More Related Videos
Related Concept Videos
Lung Capacity
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
Diffusion
Diffusion
Diagnosing Acidosis and Alkalosis
First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2 and...
Bone Formation by Endochondral Ossification

