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[Multiple Pulmonary Inflammatory Myofibroblastic Tumor].

Toshihiro Ikeda1, Jun Nakano, Yoshio Kushida

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Summary
This summary is machine-generated.

A prolonged cough led to the diagnosis of inflammatory myofibroblastic tumor in a 67-year-old man. Steroid therapy effectively managed disease exacerbation, preventing further tumor growth.

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Area of Science:

  • Pulmonology
  • Oncology
  • Pathology

Background:

  • A 67-year-old male presented with persistent cough, leading to the discovery of multiple bilateral lung lesions via chest computed tomography (CT).
  • Initial transbronchial lung biopsy was inconclusive for malignancy, and antibiotic treatment proved ineffective.

Observation:

  • Surgical resection of a lung lesion confirmed inflammatory myofibroblastic tumor (IMT).
  • Six months post-surgery, the patient experienced symptom exacerbation and lesion enlargement, as evidenced by chest CT.

Findings:

  • High-dose corticosteroid therapy (methylprednisolone pulse) resulted in symptom improvement and lesion size reduction.
  • Maintenance oral prednisolone (10 mg/day) has prevented disease recurrence or progression since the initial steroid treatment.

Implications:

  • This case highlights inflammatory myofibroblastic tumor as a rare but treatable cause of lung lesions.
  • Corticosteroid therapy demonstrates efficacy in managing symptomatic exacerbations of pulmonary IMT, suggesting a role in long-term disease control.