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Updated: Jan 22, 2026

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
Published on: April 1, 2018
Temporal Variability-Based Functional Brain Lateralization Study in ADHD
1Nanjing University of Science and Technology, P.R. China.
Abstract:
Objective: The aim of this work is to explore the relationship between temporal variability and brain lateralization in ADHD. Method: The temporal variabilities of 116 brain regions based on resting-state functional magnetic resonance imaging (rs-fMRI) data were calculated for analysis. Results: Between-group comparison revealed that in comparison with the controls, ADHD participants showed significantly higher temporal variability in the left superior frontal gyrus (medial), left rectus gyrus, left inferior parietal lobule and angular gyrus, and lower temporal variability in the amygdala, left caudate and putamen. Besides, ADHD patients exhibited significantly increased leftward lateralization in the orbitofrontal cortex (inferior), and decreased rightward lateralization in the orbitofrontal cortex (medial) and rectus gyrus, compared with controls. Lateralization indices were also found to be related with clinical characteristics of ADHD patients. Conclusion: Our results may help us deeper in understanding the pathology of ADHD.
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