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Correlation Between Apparent Diffusion Coefficient Values of the Renal Parenchyma and Estimated Glomerular Filtration

Shanigarn Thiravit¹, Paphatsanan Suwanchatree¹, Peenida Skulratanasak²

¹From the Division of Diagnostic Radiology, Department of Radiology.

Journal of Computer Assisted Tomography

|July 4, 2019

Abstract

Objective:

To evaluate the relationship between the apparent diffusion coefficient (ADC) values of renal parenchyma and estimated glomerular filtration rates (eGFR).

Methods:

Data on 216 patients examined by 3-T magnetic resonance imaging for various reasons were retrospectively collected.

Results:

There was a significant linear correlation between the ADC values and eGFRs (r = 0.254, P < 0.001). The ADC values in patients with an eGFR of less than 60 mL/min per 1.73 m were significantly lower than those with an eGFR of 60 mL/min per 1.73 m or greater. The mean ADC value of patients with grouped stage 2 disease was significantly higher than those with grouped stage 3 of chronic kidney disease (P < 0.01).

Conclusions:

The ADC value of renal parenchyma may be a promising marker for the determination of patients with normal to mild reduction in renal function (eGFR ≥60 mL/min per 1.73 m) versus those with a moderate to severe reduction in renal function (eGFR <60 mL/min per 1.73 m).

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