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Factors associated with gestational breast cancer: case-control study
Denise Leite Maia Monteiro1, Camila Lattanzi Nunes1, Nádia Cristina Pinheiro Rodrigues2
1Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro. Av. Professor Manoel de Abreu 500, Vila Isabel. 20550-170 Rio de Janeiro RJ Brasil. denimonteiro2@yahoo.com.br.
Ciencia & Saude Coletiva
|July 4, 2019
Summary
Gestational breast cancer (GBC) risk increases for mothers over 30 years old at first pregnancy. Lower educational attainment also significantly elevates GBC risk in pregnant individuals.
Area of Science:
- Oncology
- Maternal Health
- Epidemiology
Background:
- Gestational breast cancer (GBC) affects 1 in 3,000-10,000 pregnancies.
- Identifying GBC risk factors is crucial for early detection and management.
Purpose of the Study:
- To investigate sociodemographic, reproductive, and health-related risk factors for gestational breast cancer.
- To analyze the association between maternal age at first pregnancy and GBC risk.
Main Methods:
- A case-control study involving 21 GBC cases and 42 controls.
- Data collected via medical records, including reproductive and obstetrical history.
- Conditional logistic regression used to calculate odds ratios.
Main Results:
- Maternal age over 30 years at first pregnancy was significantly associated with GBC (p = 0.03).
- Each additional year of maternal age at first pregnancy increased GBC risk by 27% (p < 0.02).
- Lower levels of schooling were linked to a substantially higher risk of GBC (OR = 8.49).
Conclusions:
- Advanced maternal age at first pregnancy is a confirmed risk factor for GBC.
- Lower educational attainment is strongly associated with an increased risk of GBC.
- These findings highlight key demographic factors influencing GBC risk.
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