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Updated: Jan 22, 2026

Using Whole Mount in situ Hybridization to Link Molecular and Organismal Biology
Published on: March 31, 2011
From Molecular Understanding to Organismal Biology of N-Terminal Acetyltransferases
1Institute for Basic Research in Developmental Disabilities (IBR), Staten Island, NY 10314, USA; Biology PhD Program, The Graduate Center, The City University of New York, NY 10016, USA.
Abstract:
In this issue of Structure, Deng et al. (2019) determine the structure of the yeast N-terminal acetyltransferases Naa10 and Naa50 in complex with Naa15 and demonstrate that Naa50 has negligible catalytic activity on its own but modulates Naa10/Naa15. This study provides insights into mechanisms involving amino-terminal acetylation of proteins.
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