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Nationwide Survey for Application of ROME IV Criteria and Clinical Practice for Functional Constipation in Children
Hyo Jeong Jang1, Ju Young Chung2, Ji Hyun Seo3
1Department of Pediatrics, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Insights
Pediatricians show varied awareness and application of ROME IV criteria for functional constipation (FC). Significant differences exist in diagnostic practices and treatment preferences between pediatric gastroenterologists (PGs) and general pediatricians.
Area of Science:
- Pediatrics
- Gastroenterology
- Clinical Practice Research
Background:
- Investigates awareness and application of ROME IV criteria for functional constipation (FC) in pediatric real-world practices.
- Assesses practice differences between pediatric gastroenterologists (PGs) and general pediatricians.
Purpose of the Study:
- To evaluate current adherence to ROME IV criteria for pediatric FC diagnosis and management.
- To identify disparities in clinical approaches between specialist and general pediatricians.
Main Methods:
- A nationwide questionnaire survey was distributed to 500 pediatricians.
- Data collected from 239 respondents, including 60 pediatric gastroenterologists, on diagnosis and management of pediatric FC.
Main Results:
- Only 16.6% of pediatricians were aware of the exact ROME IV criteria.
- Pediatric gastroenterologists demonstrated higher rates of perianal/digital rectal examinations and longer treatment durations (>6 months).
- Lactulose and polyethylene glycol (PEG) 4000 were preferred by PGs, while general pediatricians also commonly prescribed probiotics.
Conclusions:
- Observed discrepancies between clinical practice and ROME IV criteria for functional constipation.
- Significant differences in diagnostic and treatment approaches exist between pediatric gastroenterologists and general pediatricians.
- Findings can inform the development of practice guidelines and educational programs for pediatric FC.
Background:
This study aimed to investigate the awareness and application of ROME IV criteria for functional constipation (FC) in real-world practices and assessed differences between pediatric gastroenterologists (PGs) and general pediatricians.
Methods:
A total of 239 (47.8%) out of 500 nationwide pediatricians answered a questionnaire for diagnosis and management of pediatric FC; 60 were PGs (75% of total PGs in Korea).
Results:
A total of 16.6% of pediatricians were aware of the exact ROME IV criteria. Perianal examination and digital rectal examination were practiced less, with a higher tendency among PGs (P < 0.001). Treatment duration was longer among PGs for > 6 months (63.8%) than < 3 months among general pediatricians (59.2%, P < 0.001). Fecal disimpaction and rectal enema were practiced among 78.8% and 58.5% of pediatricians, respectively. High dose medication for initial treatment phase was prescribed by 70.7% of pediatricians, primarily within the first 2 weeks (48.3%). The most commonly prescribed medications in children aged > 1-year were lactulose (59.1%), followed by polyethylene glycol (PEG) 4000 (17.7%), and probiotics (11.8%). Prescription priority significantly differed between PGs and general pediatricians; lactulose or PEG 4000 were most commonly prescribed by PGs (89.7%), and lactulose or probiotics (75.7%) were prescribed by general pediatricians (P < 0.001). For patients aged < 1-year, lactulose (41.6%) and changing formula (31.7%) were commonly prescribed. Most participants recommended diet modification, and PGs more frequently used defecation diary (P = 0.002).
Conclusion:
Discrepancies between actual practice and Rome IV criteria and between PGs and general pediatricians were observed. This survey may help construct practice guidelines and educational programs for pediatric FC.
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