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Updated: Sep 9, 2026

Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
Published on: November 3, 2014
[Basic phospholipase from the venom of Naja nigricollis is cytotoxic]
S Chwetzoff1, M Takeshi, P Fromageot
1Département de Biologie, C.E.N. Saclay, Gif-sur-Yvette.
Abstract:
The basic phospholipase A2 purified from the venom of Naja nigricollis (Institut Pasteur), possesses an intense cytotoxic activity toward fetal cells from FL strain. At a concentration equal to 1.6 x 10(-6) M, the PLA2 lyses 50% of the cells present in a suspension containing 3.5 x 10(6) cells per millilitre. Other PLA2 from various origins do not exhibit such cytotoxic activity.
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