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[Presence of a nerve growth factor-like immunoreactivity in auditory receptors during postnatal development in the
1Université Blaise-Pascal, Laboratoire de Neurobiologie, Ensemble scientifique des Cézeaux, Aubière.
Abstract:
The presence of nerve growth factor (NGF) was investigated in the rat cochlea from birth to the adult stage, using immunohistochemical techniques NGF-like protein could be detected in the organ of Corti from birth up to day 8 and located within the hair cells, above the nuclei. No NGF-like immunoreactivity could be detected in the spiral ganglion. These results suggest that NGF may have a neurotropic action in the developing rat cochlea.