Structural equation modeling of associations between night work and glycemic levels
Aline Silva-Costa1,2, Lúcia Rotenberg3, Valéria Troncoso Baltar4
1Departamento de Saúde Coletiva , Universidade Federal do Triângulo Mineiro (UFTM), Uberaba , MG , Brasil.
Objective:
Different pathways may lead from night work to metabolic diseases, including type 2 diabetes. This study aimed to explore the direct and indirect pathways from night work to glycemic levels, considering the role of physical activity, waist circumference and snacking using data from ELSA-Brasil.
Materials And Methods:
A structural equation model was used to confirm the pathways from night work to glycemic levels. The latent variable, "glycemic levels", included fasting glucose, glycated hemoglobin and 2-hour plasma glucose.
Results:
A total of 10.396 participants were included in the analyses. The final model showed that among women, night work was associated with increased glycemic levels. A statistical significant association between night work and glycemic levels mediated by waist circumference was observed among women and men.
Conclusions:
The association between night shift and glycemic levels can be interpreted as an important step toward understanding the pathways that could explain night work as a risk factor for diabetes using epidemiological data.
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