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Is Alzheimer's Disease a Neurogenesis Disorder?
Se Hoon Choi1, Rudolph E Tanzi1
1Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Cell Stem Cell
|July 5, 2019
Abstract:
The existence of adult hippocampal neurogenesis (AHN) in humans has been controversial. However, recent reports have detected AHN in aged adults and patients with mild cognitive impairment and Alzheimer's disease (AD), suggesting that therapies aimed at promoting AHN may be useful for the prevention and treatment of AD.