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Updated: Jan 22, 2026

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
Published on: April 8, 2020
Light triggered encapsulation and release of C60 with a photoswitchable TPE-based supramolecular tweezers
Mousumi Samanta1, Anushri Rananaware2, Dinesh N Nadimetla3
1Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, Nadia, WB, 741246, India.
Abstract:
Stimuli responsive hosts for C60 can control its binding and release on demand. A photoswitchable TPE based supramolecular host can encapsulate C60 in the Z-form with a markedly different visual change in the colour. In addition, the Z-1 bound C60 has been characterized by various spectroscopic methods and mass spectrometry. Upon exposure to visible light (>490 nm), the host switches to the E-form where the structural complementarity with the guest is destroyed as a result of which the C60 is disassembled from the host. The results described herein reveals an actionable roadmap to pursue further advances in component self-assembly particularly light-induced association and dissociation of a guest molecule.
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