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Related Concept Videos

Resistors In Series01:10

Resistors In Series

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A resistor is an ohmic device that limits the flow of charge in a circuit. Most circuits have more than one resistor. If several resistors are connected together and connected to a battery, the current supplied by the battery depends on the equivalent resistance of the circuit. The equivalent resistance of a combination of resistors depends on both their individual values and how they are connected. The simplest combination of resistors is the series combination. 
In a series circuit, the...
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Series Resonance01:17

Series Resonance

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The RLC circuit impedance is defined as the ratio of the supply voltage to the circuit current. Resonance in such a circuit occurs when the imaginary part of this impedance equals zero. This specific condition means that the inductive reactance is exactly equal to the capacitive reactance. The frequency at which this happens is known as the resonant frequency. Mathematically, the resonant frequency is inversely proportional to the square root of the product of the inductance (L) and capacitance...
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Trigonometric Fourier series01:17

Trigonometric Fourier series

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Fourier series is a foundational mathematical technique that decomposes periodic functions into an infinite series of sinusoidal harmonics. This method enables the representation of complex periodic signals as sums of simple sine and cosine functions, facilitating their analysis and interpretation in various fields, including signal processing, acoustics, and electrical engineering.
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...
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Convergence of Fourier Series01:21

Convergence of Fourier Series

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The Fourier series is a powerful mathematical tool for representing periodic signals as an infinite sum of complex exponentials. In practice, this infinite series is truncated to a finite number of terms, yielding a partial sum. This truncation makes the approximation of the signal feasible but introduces certain challenges, particularly near discontinuities, known as the Gibbs phenomenon.
The Gibbs phenomenon refers to the persistent oscillations and overshoots that occur near discontinuities...
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Series R—L Circuit Transients01:22

Series R—L Circuit Transients

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In a series resistor-inductor (R-L) circuit, closing the switch at the start of the time period simulates a three-phase short circuit, a fault condition where all three phases of an unloaded synchronous machine are short-circuited. When there is no fault impedance and no initial current, the initial voltage is determined by the phase angle of the source voltage.
Using Kirchhoff's Voltage Law (KVL) to analyze this circuit helps determine the total asymmetrical fault current, which consists...
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Series and Parallel Capacitors01:14

Series and Parallel Capacitors

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Capacitors, fundamental components in electronic circuits, can be connected in series and/or parallel configurations. Each configuration has different impacts on the overall behavior of the circuit.
First, consider capacitors connected in series to a battery. In this configuration, the plate connected to the battery's positive terminal develops a positive charge, while the plate attached to the negative terminal becomes negatively charged. An equal magnitude of charge is induced on the...
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Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
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Pediatric leukemia cutis: A case series.

Elena Corina Andriescu1, Carrie C Coughlin2, Carol E Cheng3

  • 1McGovern Medical School, University of Texas, Houston, Texas.

Pediatric Dermatology
|July 6, 2019
PubMed
Summary

Pediatric leukemia cutis (LC) often mimics other skin conditions, making diagnosis challenging. Early recognition of LC in children is crucial as it frequently accompanies systemic leukemia and can alter treatment.

Keywords:
acute lymphoblastic leukemiaacute myeloid leukemiaaleukemic leukemia cutispediatric leukemia cutis

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Area of Science:

  • Pediatric Dermatology
  • Hematology Oncology
  • Dermatopathology

Background:

  • Pediatric leukemia cutis (LC) presents diagnostic challenges due to its varied appearance, often resembling other dermatologic conditions.
  • Limited large-scale studies exist on childhood LC, hindering comprehensive understanding.

Observation:

  • A retrospective case series analyzed 31 pediatric patients with leukemia cutis.
  • Data was collected from Boston Children's Hospital and the Children's Hospital of Philadelphia.

Findings:

  • Leukemia cutis lesions varied in number and morphology, commonly affecting the head and lower extremities.
  • LC typically occurred concurrently with initial systemic leukemia episodes, particularly acute myeloid leukemia.
  • Diagnosis of LC influenced treatment timing and therapeutic strategies.

Implications:

  • Physicians should maintain a high index of suspicion for pediatric LC due to its diverse presentation.
  • Identifying LC is critical as its presence can significantly impact the management of systemic leukemia in children.