Management of cardiogenic shock complicating myocardial infarction: an update 2019

Holger Thiele1,2, E Magnus Ohman3, Suzanne de Waha-Thiele4

  • 1Department of Internal Medicine/Cardiology, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, 04289 Leipzig, Germany.

Insights

Cardiogenic shock (CS) following acute myocardial infarction (AMI) has high mortality. This review examines current, state-of-the-art treatments for CS complicating AMI, focusing on evidence-based strategies.

Area of Science:

  • Cardiology
  • Critical Care Medicine

Background:

  • Cardiogenic shock (CS) is the leading cause of mortality in acute myocardial infarction (AMI) patients.
  • Despite advances, CS mortality remains high at 40-50% over the past two decades.
  • Current management includes revascularization, vasopressors, inotropes, fluids, and mechanical support, but evidence is limited.

Purpose of the Study:

  • To provide an updated review on the management of cardiogenic shock complicating AMI.
  • To highlight state-of-the-art treatment strategies based on current evidence.

Main Methods:

  • Literature review of current management strategies for CS in AMI.
  • Focus on evidence supporting different treatment modalities.

Main Results:

  • Early revascularization is a key treatment for CS in AMI.
  • Evidence for other interventions like vasopressors, inotropes, and fluids is limited.
  • Intra-aortic balloon pumping shows limited effectiveness.

Conclusions:

  • Effective management of CS in AMI requires a comprehensive approach.
  • Further research is needed to establish robust evidence for various treatment strategies.
  • State-of-the-art care focuses on timely revascularization and tailored supportive therapies.

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