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Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
Published on: July 1, 2021
18F-FDG PET/MR in an Atypical Pediatric Solid Pseudopapillary Pancreatic Tumor
Annachiara Cavaliere1, Chiara Giraudo1, Monica Zuliani1
1From the Radiology Institute.
Abstract:
MR and F-FDG PET/MR images of a 15-year-old boy with recurrent mild abdominal pain and hyperamylasemia demonstrating a pancreatic head lesion hypointense on the T1-weighted and slightly hyperintense on the T2-weighted images, with very small pseudocystic areas, restricted diffusion on the apparent diffusion coefficient map, and focal FDG uptake. No other pathologic findings such as enlarged lymph nodes, vascular invasion, metastases, dilatation of the main pancreatic duct, or pathologic uptake of the parotid glands were detected. The MR features, even if atypical, together with the focal uptake, allowed the diagnosis of pediatric solid pseudopapillary pancreatic tumor, which was then confirmed by histology.
Insights
A rare pediatric solid pseudopapillary pancreatic tumor was diagnosed in a 15-year-old boy using advanced MR and F-FDG PET/MR imaging. Imaging findings, including focal uptake, confirmed the diagnosis, which was histologically verified.
Area of Science:
- Oncologic Imaging
- Pediatric Radiology
- Gastroenterology
Background:
- Solid pseudopapillary pancreatic tumor (SPPT) is a rare, low-grade malignant neoplasm predominantly affecting young women.
- Diagnosis in pediatric patients is infrequent and can be challenging due to atypical presentations.
Observation:
- A 15-year-old male presented with recurrent abdominal pain and hyperamylasemia.
- MR and F-FDG PET/MR imaging revealed a pancreatic head lesion with specific signal characteristics, small pseudocystic areas, restricted diffusion, and focal FDG uptake.
Findings:
- The imaging features, while atypical for SPPT, combined with focal FDG uptake, were suggestive of the diagnosis.
- Histological confirmation established the diagnosis of pediatric solid pseudopapillary pancreatic tumor.
- No metastatic disease, lymphadenopathy, or ductal dilatation was observed.
Implications:
- This case highlights the utility of integrated MR and F-FDG PET/MR imaging in diagnosing rare pediatric pancreatic neoplasms.
- Advanced imaging can aid in the early detection and characterization of SPPT, even with atypical imaging features.
- Accurate diagnosis is crucial for appropriate management and improved outcomes in pediatric oncology.
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