Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Abnormal Proliferation02:23

Abnormal Proliferation

5.1K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.1K
Histone Variants at the Centromere02:30

Histone Variants at the Centromere

5.0K
Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3...
5.0K
Common Ion Effect03:24

Common Ion Effect

46.0K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
46.0K
Normal Stress01:19

Normal Stress

1.4K
Normal stress is a type of stress that occurs when forces act perpendicular, or normal, to a material's cross-sectional area. This stress often arises in structures when subjected to axial loading, which is the application of force along the axis of an object. A practical example of this can be found in bridge truss members.
When a rod is under axial loading, the internal forces and corresponding stress are normal to the plane of the section, so it is termed normal stress. It's important to...
1.4K
Normal Distribution01:11

Normal Distribution

16.7K
The normal, a continuous distribution, is the most important of all the distributions. Its graph is a bell-shaped symmetrical curve, which is observed in almost all disciplines. Some of these include psychology, business, economics, the sciences, nursing, and, of course, mathematics. Some instructors may use the normal distribution to help determine students’ grades. Most IQ scores are normally distributed. Often real-estate prices fit a normal distribution. The normal distribution is...
16.7K
Respiratory System Abnormal Finding I: Inspection and Percussion01:30

Respiratory System Abnormal Finding I: Inspection and Percussion

790
Respiratory system abnormalities are a significant concern in healthcare due to their potential to indicate underlying severe conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, and pneumonia. These abnormalities can often be detected through physical examination methods like inspection and percussion.
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
790

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying cognitive effort's impact on suppression of epilepsy-associated after discharges.

Frontiers in network physiology·2026
Same author

Trends in Industry-Sponsored Research Payments and General Payments to Neurologists: Open Payments Program 2015-2023.

Neurology. Clinical practice·2026
Same author

Deep Learning for the Prediction of Treatment Responses in Individuals With Epilepsy: Can We Get to Seizure Freedom Faster?

Neurology·2025
Same author

Eigenvector biomarker for prediction of epileptogenic zones and surgical success from interictal data.

Frontiers in network physiology·2025
Same author

Driving in people with seizures and epilepsy.

The Lancet. Neurology·2025
Same author

Improving the tolerability of antiseizure medications: When and how to use cenobamate and other new antiseizure medications.

Epilepsia·2025

Related Experiment Video

Updated: Jan 22, 2026

Recording and Modulation of Epileptiform Activity in Rodent Brain Slices Coupled to Microelectrode Arrays
10:24

Recording and Modulation of Epileptiform Activity in Rodent Brain Slices Coupled to Microelectrode Arrays

Published on: May 15, 2018

15.3K

Normal Variants Are Commonly Overread as Interictal Epileptiform Abnormalities.

Joon Y Kang1, Gregory L Krauss1

  • 1Department of Neurology/Epilepsy Division, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|July 6, 2019
PubMed
Summary
This summary is machine-generated.

Electroencephalographers can misclassify benign EEG variants like wicket spikes as seizures. Careful review of clinical history and EEG patterns helps avoid misdiagnosis and treatment delays for conditions like nonepileptic seizures.

More Related Videos

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture
09:06

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture

Published on: December 22, 2016

10.1K
Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

21.1K

Related Experiment Videos

Last Updated: Jan 22, 2026

Recording and Modulation of Epileptiform Activity in Rodent Brain Slices Coupled to Microelectrode Arrays
10:24

Recording and Modulation of Epileptiform Activity in Rodent Brain Slices Coupled to Microelectrode Arrays

Published on: May 15, 2018

15.3K
Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture
09:06

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture

Published on: December 22, 2016

10.1K
Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

21.1K

Area of Science:

  • Neurology
  • Clinical Neurophysiology

Background:

  • Electroencephalography (EEG) interpretation is crucial for diagnosing neurological disorders.
  • Benign EEG variants can be mistaken for epileptiform discharges, leading to diagnostic challenges.

Purpose of the Study:

  • To highlight the potential for misclassification of benign EEG variants as epileptiform discharges.
  • To emphasize the importance of distinguishing these variants to prevent diagnostic delays and inappropriate treatment.

Main Methods:

  • Review of common benign EEG variant patterns, including wicket spikes, small sharp spikes, and rhythmic mid-temporal theta of drowsiness.
  • Analysis of clinical scenarios where misclassification can occur, such as in elderly patients with syncope.

Main Results:

  • Benign variants like wicket spikes can be misinterpreted as epileptiform activity.
  • Misclassification can lead to delayed diagnosis of conditions such as psychogenic nonepileptic seizures, anxiety/panic disorders, and near syncope.

Conclusions:

  • Cautious interpretation of EEG, especially during drowsiness, is essential to avoid misdiagnosing seizures.
  • Integrating EEG findings with clinical history is vital for accurate diagnosis and appropriate patient management.