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Is There a Role for Ileal Pouch Anal Anastomosis in Crohn's Disease?
Nicole E Lopez1, Karen Zaghyian1, Phillip Fleshner1
1Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California.
Clinics in Colon and Rectal Surgery
|July 6, 2019
Abstract:
Traditionally, surgical interventions for colonic Crohn's disease (CD) have been limited to total abdominal colectomy and ileorectal anastomosis, or total proctocolectomy with end ileostomy if there is rectal involvement. However, improved understandings of the biology of CD, as well as the development of biologic therapies, have enabled more limited resections. Here, we review the indications for, and limitations of, specific procedures aiming to preserve intestinal continuity in colonic CD.