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Cancer driver genes: a guilty by resemblance doctrine

Emilie Ramsahai1, Vrijesh Tripathi1, Melford John2

  • 1Department of Mathematics and Statistics, The University of the West Indies, St. Augustine, Trinidad and Tobago.

Peerj
|July 6, 2019
PubMed
Summary

A new method identifies novel cancer driver genes by analyzing biological pathways, not just mutation frequency. This approach accelerates discovery and finds previously missed targets for cancer drug development.

Keywords:
CancerNetwork topologyNovel driver genesPathwaysSignal transductionm-reach

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