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IL-7 is a Key Driver Cytokine in Spondyloarthritis?
Rafaela Silva Guimarães Gonçalves1, Angela Luzia Branco Pinto Duarte1
1Hospital das Clínicas de Pernambuco, Brazil.
Abstract:
The rationale for a type 17 signature in the pathogenesis of spondyloarthritis (SpA) has been increasing and being ratified in studies recently. IL-7 is a cytokine whose ability to stimulate IL-17 production in both innate and adaptive immunity cells has made it a promising target not only for a better understanding of the disease as well as an important potential therapeutic target in patients with SpA.
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