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Updated: Jan 22, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Recent advances in the synthesis of axially chiral biaryls via transition metal-catalysed asymmetric C-H
Gang Liao1, Tao Zhou1, Qi-Jun Yao1
1Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang 310027, China. bfshi@zju.edu.cn.
Abstract:
Axially chiral biaryl motifs are widely present in natural products and pharmaceuticals. Moreover, they have been broadly used as privileged ligands in asymmetric catalysis. Over the past few decades, the efficient synthesis of axially chiral biaryls has been a research topic of great interest. This feature article will provide an overview of recent advances in the synthesis of these chiral skeletons via transition metal-catalysed asymmetric C-H functionalization.
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