Related Experiment Video
Updated: Jan 22, 2026

Isolation of Lymphocytes from Mouse Genital Tract Mucosa
Published on: September 3, 2012
[A man with backache and a genital skin lesion]
Ellen R M Scheepers1,2, Annebeth E Flinterman3, Noortje Thielen1
1Diakonessenhuis, afd. Interne Geneeskunde, Utrecht.
Abstract:
A 72-year-old man was admitted to hospital because of backache. Physical examination also revealed a genital skin lesion with inguinal lymphadenopathy. Skin biopsy showed an infiltrating adenoma, arising from extramammary Paget disease. MRI of the vertebral column revealed multiple osteolytic lesions, likely metastases. The patient was diagnosed with metastatic extramammary Paget disease, which has a poor prognosis.
Related Concept Videos
External Female Genitals
Psychosexual Stages of Personality: Genital
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Sensory Functions of the Skin
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...

