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Updated: Jan 22, 2026

The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
Published on: November 2, 2016
Feeding arteries and arteriovenous shunt for discrimination of soft tissue tumors
Gang Wu1, Hao Yang2, Xiaoming Li1
1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei.
Abstract:
Time resolved magnetic resonance angiography with interleaved stochastic trajectories (TWIST) allows for identification of tumor feeding arteries and arteriovenous shunt (AVS). We used TWIST to obtain number of feeding arteries (NFA) and detect AVS for 43 cases of pathology-confirmed soft tissue tumors. We compared normalized number of feeding arteries (nNFA) and AVS between malignant and benign tumors, and found nNFA was significantly greater in malignant tumors versus benign tumors (2.1 vs 1.3, P < .05). The incidence of AVS was significantly higher in malignant tumors versus benign tumors (87.5% vs 10.5%, P < .05). TWIST derived nNFA and AVS could be useful in the discrimination of benign and malignant soft tissue tumors.
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