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Updated: Jan 22, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Optical coherence tomography angiography in Purtscher-like retinopathy associated with dermatomyositis: a case report
D Vezzola1,2, D Allegrini3, M R Romano2
1Eye Unit, University Hospital Maggiore della Carita, Novara, Italy.
Purpose:
To describe a multimodal imaging diagnosis of retinopathy in dermatomyositis.
Case Presentation:
A 21-year-old white woman with a history of fatigue and a cutaneous rash complained of visual impairment in her left eye. A funduscopic examination showed multiple confluent cotton-wool spots in both eyes. Swept source-optical coherence tomography presented macular edema in both eyes; optical coherence tomography angiography revealed superficial and deep capillary occlusion in all areas affected by cotton-wool spots; and fluorescein angiography showed vascular walls enhancement, veins dilatation, and capillary leakage. After large doses of intravenously administered glucocorticoid therapy, followed by a cyclophosphamide regimen, best corrected visual acuity returned to 20/20 in both eyes.
Conclusions:
This case report presents optical coherence tomography angiography clinical findings in a rare case of dermatomyositis-associated retinopathy, remarking the importance of a multi-imaging approach for a correct diagnosis and treatment of eye injuries, in order to avoid serious complications and permanent sequelae.
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