Related Experiment Video
Updated: Aug 17, 2026

11:11
Construction and Characterization of a Novel Vocal Fold Bioreactor
Published on: August 1, 2014
Hydron gel implants in vocal cords
1Department of Phoniatrics, Medical Faculty Hospital-Charles University, Plzen, Czechoslovakia.
Summary
A novel surgical technique implants a Hydron rod to correct glottic insufficiency, significantly improving voice quality and reducing vocal fatigue in patients. This minimally invasive procedure offers effective voice restoration.
Area of Science:
- Otolaryngology
- Speech Pathology
- Biomaterials Science
Background:
- Vocal fold insufficiency can lead to significant voice impairment and reduced quality of life.
- Current treatment options for glottic insufficiency may have limitations or undesirable side effects.
- A minimally invasive surgical approach is needed to effectively address vocal fold closure issues.
Purpose of the Study:
- To describe a new surgical operation for correcting insufficient glottic closure.
- To evaluate the efficacy of Hydron rod implantation for voice improvement.
Main Methods:
- A submucosal tunnel was created in the vocal mucosa using specialized instruments.
- A spindle-form Hydron gel rod was implanted via direct laryngoscopy under general anesthesia.
- The operative microscope was utilized for enhanced visualization and illumination during the procedure.
Main Results:
- The operation was successfully performed on 40 patients.
- Sound analysis demonstrated a significant improvement in voice quality.
- Patients reported a considerable subjective decrease in symptoms, particularly voice fatiguability.
Conclusions:
- Hydron rod implantation is an effective surgical treatment for glottic insufficiency.
- The procedure leads to measurable improvements in voice quality and patient-reported outcomes.
- This technique offers a promising solution for patients suffering from vocal fold closure deficits.

