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Updated: Jan 22, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus: Clues to early diagnosis
Lai Yin Law1, Irene Tan2, Michael Prowse3
1Neuroimmunology Clinic, Concord Hospital, University of Sydney, NSW, Australia.
Abstract:
A case of progressive multifocal leukoencephalopathy (PML) occurring on low dose immunosuppression for systemic lupus erythematosus (SLE) and Sjogren's syndrome (SS) is presented. Neurologic changes in patients with SLE or SS should not be assumed to be a disease manifestation. Importantly, serious opportunistic infections such as PML can occur in minimally immunosuppressed rheumatic patients. Early diagnosis, facilitated by scrutiny of MRI findings, should trigger measures to reconstitute immunity in an otherwise fatal disease.
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