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Updated: Jan 22, 2026

Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
Cerebral venous thrombosis: a rare complication of herpes simplex encephalitis
M Vedani1, O Toubas2, M Hentzien1
1CHU Reims, Unité des Maladies Infectieuses et Tropicales, Hôpital Robert Debré, 51092, Reims, France.
Abstract:
We report a case of classic HSE with early neurological relapse 7 days after onset of acyclovir treatment secondary to cerebral venous thrombosis (CVT). The development of CVT after meningoencephalitis has been described with neurotropic viruses such as HSV, HIV, or enteroviruses and also bacterial or fungal agents. CVT is probably the consequence of the inflammation secondary to these infections. A diagnosis of CVT, although rarely described, should be systematically suspected in patients with HSE who present no or only moderate improvement, or early relapse of symptoms despite adapted acyclovir treatment.
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