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Updated: Jan 22, 2026

Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow
Published on: March 15, 2021
Transcranial Doppler and Optic Nerve Sonography
Frank A Rasulo1, Rita Bertuetti2
1Department of Medical and Surgical Specialties, Radiological Sciences and Public Health. Division of Anesthesiology, Intensive Care and Emergency Medicine, University of Brescia at Spedali Civili Hospital, Brescia, Italy; Division of Anesthesiology, Intensive Care, and Emergency Medicine, University of Brescia at Spedali Civili Hospital, Brescia, Italy.
Brain ultrasound, or TCCD, is a versatile bedside tool for assessing cerebral blood flow. It aids in diagnosing various neurological conditions and evaluating hemodynamic status in diverse clinical settings.
Area of Science:
- Neurology
- Vascular Medicine
- Medical Imaging
Background:
- Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) are bedside ultrasound techniques.
- TCCD offers both cerebral blood flow velocity (CBFV) and B-mode imaging.
- Brain ultrasound (TCCD) is applicable in diverse settings from emergency to intensive care.
Purpose of the Study:
- To review the broad applications of brain ultrasound (TCCD).
- To highlight its utility in neurologic and non-neurologic conditions.
- To detail its role in assessing cerebrovascular health and diagnosing critical conditions.
Main Methods:
- Review of existing literature on TCCD applications.
- Synthesis of data regarding TCCD's diagnostic capabilities.
- Categorization of TCCD uses in neurocritical care and beyond.
Main Results:
- TCCD is crucial for evaluating subarachnoid hemorrhage, traumatic brain injury, and stroke.
- It detects vessel occlusion, assesses cerebrovascular reactivity, and estimates intracranial pressure.
- TCCD confirms cerebral circulatory arrest and aids in diagnosing brain death.
Conclusions:
- Brain ultrasound (TCCD) is a valuable, non-invasive tool for neurological and hemodynamic assessment.
- Its applications extend to perioperative care, sickle cell disease, and diagnosing cerebrovascular abnormalities.
- TCCD plays a significant role in critical care, including the diagnosis of brain death.
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