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Updated: Jan 22, 2026

Measurement of Tumor T2* Relaxation Times after Iron Oxide Nanoparticle Administration
Published on: May 19, 2023
T2* Mapping Techniques: Iron Overload Assessment and Other Potential Clinical Applications
Katia Menacho1, Amna Abdel-Gadir2, James C Moon3
1Barts Heart Centre, The Cardiovascular Magnetic Resonance Imaging Unit, Institute of Cardiovascular Science, University College London, St Bartholomew's Hospital, 2nd Floor, King George V Block, West Smithfiled, London EC1A 7BE, UK.
Abstract:
T2* mapping techniques has evolved significantly since their introduction in the early 2000s and a significant amount of evidence has been gathered to support their clinical routine use for iron overload assessment. This article focuses on the most important aspects of how to perform T2* imaging, from acquisition, to postprocessing, to analyzing the data with clinical concentration. Newer techniques have made T2* mapping more robust and accurate, allowing a broader use of this technique for noncontrast ischemia imaging based on blood oxygen levels, in addition to evaluation of intramyocardial hemorrhage and microvascular obstruction.
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