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Updated: Jan 22, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
Published on: May 6, 2010
Transcribing Memories in Genome Architecture
Katherine R Tonn Eisinger1, Anne E West1
1Duke University, Department of Neurobiology, Durham, NC 27710, USA.
Abstract:
Whether dynamic changes in genome architecture underlie transcriptional and functional plasticity in mature neurons has been technically challenging to address. A recent study (Yamada et al., Nature, 2019) exploited experimental advantages of the cerebellum to reveal cell type-specific changes in chromatin architecture that coordinate neural activity-induced changes in gene transcription and contribute to sensorimotor learning.
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