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Updated: Jan 22, 2026

Endoscopic Approach for Colloid Cyst Resection
Published on: May 23, 2025
Additional Surgical Resection After Endoscopic Resection for Patients With High-risk T1 Colorectal Cancer
Kenta Iguchi1, Hiroyuki Mushiake2, Toru Aoyama3
1Department of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
Background/Aim:
The purpose of this study was to reveal the safety and efficacy of additional surgical resection (ASR) for high-risk T1 colorectal cancer (CRC) after endoscopic resection (ER).
Patients And Methods:
We retrospectively analyzed 191 patients with high-risk T1 CRC after ER.
Results:
The ASR was performed in 176 (92.1%) patients and 15 (7.9%) rejected ASR. All patients that underwent ASR experienced R0 resection; laparoscopic surgery was performed in 159 (90.3%) patients. Clavien-Dindo complications ≥grade II occurred in 33 patients (18.8%). Anastomotic leakage (8.5%) and ileus (5.7%) were the most frequent complications. The anus function was preserved in all patients. Metastatic lymph node was detected in 21 (11.9%) patients. There were no deaths or relapses in patients with ASR. One patient without ASR (6.7%) had a lymph node recurrence.
Conclusion:
ASR was safe and effective and is recommended for high-risk T1 CRC patients after ER. A satisfactory long-term outcome can be achieved.
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