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Lipid droplet accumulation in the heart during fasting
1Department of Anatomy and Cell Biology, University of Sheffield, England.
Acta Histochemica
|January 1, 1987
Abstract:
Lipid droplet accumulation (LDA) in the myocardium in the different regions of the mouse heart was studied after varying periods of starvation. LDA appeared as early as 6 h and remained even after 72 h of starvation. Higher grades of LDA were seen in the left atrium and right ventricle. Females showed a higher degree of infiltration than males. The possible causes for the distribution of lipid droplets are discussed and it is suggested that in long-term starvation reduced oxidation of fatty acids due to mitochondrial inhibition may be a factor in the production of LDA.