Multifocal intracranial MR abnormalities in neurofibromatosis

MR imaging of four children with neurofibromatosis demonstrated areas of increased T2 signal involving widespread multifocal regions of basal ganglia and brainstem. Such abnormalities have not been previously reported. No corresponding CT abnormalities were present. These regions may represent hamartomatous or low-grade gliomatous change, and appear to be characteristic of neurofibromatosis in children.