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Related Experiment Videos

A dermatologic emergency; Sweet's syndrome.

Mustafa Korkut1

  • 1Health Science University Antalya Training and Research Hospital, Emergency Medicine Department, Turkey.

The American Journal of Emergency Medicine
|July 9, 2019
PubMed
Summary

Sweet's syndrome (SS), a rare neutrophilic dermatosis, presents with fever and painful skin lesions. Early diagnosis and corticosteroid treatment rapidly improve symptoms, even when lesions appear on lower extremities.

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Area of Science:

  • Dermatology
  • Internal Medicine

Background:

  • Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis, is a rare condition characterized by recurrent erythematous skin lesions.
  • Lesions typically manifest as papules, nodules, and plaques on the extremities, trunk, neck, and face.

Observation:

  • A 72-year-old male presented with a 10-day history of fever, generalized rash, and myalgia/arthralgia.
  • He exhibited painful erythematous plaques and serohemorrhagic bullae on his extremities and trunk.
  • Laboratory findings included leukocytosis with neutrophilia, elevated CRP, and high erythrocyte sedimentation rate.

Findings:

  • The patient was diagnosed with Sweet's syndrome based on clinical presentation, laboratory results, and skin biopsy findings.
  • Skin biopsy revealed dense dermal neutrophilic infiltrate and leukocytoclasis.
Keywords:
DermatosisEmergency departmentSweet's syndrome

Related Experiment Videos

  • The patient showed a rapid clinical improvement following systemic corticosteroid therapy.

    • Implications:

    • This case highlights the importance of recognizing Sweet's syndrome in the emergency department, even with atypical lesion distribution on lower extremities.
    • Prompt diagnosis and initiation of corticosteroid treatment are crucial for managing this rare, potentially life-threatening dermatosis.
    • Early intervention leads to rapid symptom resolution and improved patient outcomes.