autoDIAS: a python tool for an automated distortion/interaction activation strain analysis
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Updated: Jan 22, 2026

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ
Published on: August 9, 2022
Dennis Svatunek1, Kendall N Houk1
1Department of Chemistry and Biochemistry, University of California, Los Angeles, California.
Abstract:
The distortion/interaction activation strain (DIAS) analysis is a powerful tool for the investigation of energy barriers. However, setup and data analysis of such a calculation can be cumbersome and requires lengthy intervention of the user. We present autoDIAS, a python tool for the automated setup, performance, and data extraction of the DIAS analysis, including automated detection of fragments and relevant geometric parameters. © 2019 Wiley Periodicals, Inc.
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