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Updated: Jan 22, 2026

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties
Published on: January 8, 2016
Water gated contrast switching with polymer-silica hybrid nanoparticles
Juan Pellico1, Connor M Ellis1, Jack Miller2
1Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK. jason.davis@chem.ox.ac.uk.
Abstract:
Bioresponsive contrast agents can provide smart signaling in MRI. In wrapping pore functionalised Gd-DOTA mesoporous silica nanoparticles with pH-responsive poly(acrylic acid), exchange between pore and bulk water can be reversibly switched by local pH. The generated high contrast then exhibits a large amplitude switch in a manner relevant to environmentally responsive imaging.
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