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Updated: Jan 22, 2026

Inducing Post-Traumatic Epilepsy in a Mouse Model of Repetitive Diffuse Traumatic Brain Injury
Published on: February 10, 2020
Retrospective Analysis of Forensic Appraisal of Post-traumatic Epilepsy in 30 Cases
1Institute of Forensic Expertise, Dean Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China.
Abstract:
Objective To summarize the general characteristics and identification considerations of appraisal of post-traumatic epilepsy (PTE) in forensic clinical expertise. Methods Descriptive statistics were made on the general situations (age and sex), injury sites, PTE grading, clinical manifestations and blood drug concentrations of 30 cases of PTE. Chi-square test was performed on the differences of sex composition, age group incidences, injury sites, clinical manifestations and PTE grading. Fisher's exact probability method was used to test the differences in clinical manifestations and PTE grading of each site and the differences in PTE grading of different clinical manifestations. Results PTE occurred more frequently among 21 to 40 year olds, more in males than in females, and more frequently in the temporal lobe and frontal lobe. The clinical manifestations were mostly partial seizures and the PTE grading was mostly mild PTE. There were no statistical significance in the differences in distribution of clinical manifestations and PTE grading of injury sites (P>0.05). The difference in the PTE grading of different clinical manifestations had no statistical significance (P>0.05). The blood drug concentration of the three identified people did not reach the effective concentration, which affected the final identification opinion. Conclusion In the identification of PTE, in addition to strictly grasping the necessary factors of identification, such as the history of craniocerebral trauma, and epileptic seizures, it is also suggested that attention should be paid to the detection of blood drug concentration. Overall analysis and comprehensive evaluation should be made.
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