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The Effect of Daily Exercise Program on Bone Mineral Density and Cortisol Level in Preterm Infants with Very Low
Yağmur Sezer Efe1, Emine Erdem1, Tamer Güneş2
1Department of Nursing, Faculty of Health Sciences, Erciyes University, Kayseri, Turkey.
Insights
A daily exercise program positively impacts bone mineral density and cortisol levels in very low birth weight preterm infants. Neonatal nurses can integrate this exercise regimen into clinical practice for improved infant outcomes.
Area of Science:
- Neonatal care
- Pediatric exercise physiology
- Bone metabolism
Background:
- Preterm infants, especially those with very low birth weight (VLBW), are at risk for suboptimal bone development and elevated stress hormone levels.
- Early interventions are crucial for improving outcomes in this vulnerable population.
- Bone mineral density and cortisol levels are key indicators of infant health and development.
Purpose of the Study:
- To investigate the effects of a daily exercise program on bone mineral density and serum cortisol levels in VLBW preterm infants.
- To assess the impact of exercise on anthropometric measurements in this cohort.
- To provide evidence for the integration of exercise interventions in neonatal intensive care units (NICUs).
Main Methods:
- A randomized controlled double-blinded study involving 24 VLBW preterm infants in a tertiary hospital NICU.
- Participants were matched for birth weight, gestational week, and gender.
- An exercise group received a daily 7-10 minute exercise program for 30 days, with a control group receiving standard care.
- Evaluations included anthropometric measurements, tibia speed of sound (SOS) for bone mineral density, and serum cortisol levels before and after the intervention.
Main Results:
- The exercise group showed a significant increase in bone SOS values (p=0.009) and a decrease in serum cortisol levels (p=0.05).
- Percentage increases in anthropometric measurements were higher in the exercise group compared to the control group.
- The observed changes in bone SOS and cortisol levels in the exercise group were statistically significant.
Conclusions:
- A daily exercise program demonstrates a positive effect on bone mineral density (measured by SOS) and serum cortisol levels in preterm infants.
- The findings support the implementation of this exercise program by neonatal nurses in clinical practice.
- This intervention may contribute to improved bone health and stress regulation in VLBW preterm infants.
Purpose:
This randomized controlled double-blinded experimental study was carried out to determine the effects of the daily exercise program on bone mineral density and cortisol level in preterm infants with VLBW matched for birth weight, gestation week, and gender.
Design And Methods:
The study was carried out with preterm infants (n = 24) hospitalized in the NICU of a tertiary hospital. Ethical committee approval, institutional permission, parental written consent were obtained. A daily exercise program was implemented in preterm infants in the exercise group for 30 days, once a day, and continuing for 7-10 min. Before and after the study the following were evaluated in preterm infants in the exercise and control group: anthropometric measurements, tibia speed of sound (SOS) for bone mineral density, serum cortisol levels.
Results:
Serum cortisol levels (p = 0.05) were decreased, bone SOS values in the exercise group were increased (p = 0.009), after the study. The difference between pre-, post-study bone SOS and serum cortisol values of infants in the exercise group were high (p > 0.05). Percentage increases in anthropometric values in the exercise group were higher than the control group after the study (for all; p > 0.05).
Conclusions:
The daily exercise program has positive effect on bone SOS and serum cortisol values in preterm infants. Neonatal nurses can implement the daily exercise program in clinical practice. Trial registration numberClinicaltrials.govNCT03773679.
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