Extrachromosomal circular DNAs: an extra piece of evidence to depict tumor heterogeneity

Ishita Tandon1, Roshni Pal1, Jayanta K Pal1

  • 1Cancer & Translational Research Lab, Dr DY Patil Biotechnology & Bioinformatics Institute, Dr DY Patil Vidyapeeth, Pune, Maharashtra 411033, India.

Future Science OA
|July 10, 2019
PubMed

Related Concept Videos

The Evidence for Evolution02:55

The Evidence for Evolution

Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
47.7K
Oxygen Delivering System III: Tracheostomy and T-piece01:23

Oxygen Delivering System III: Tracheostomy and T-piece

Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
5.7K
Deformation in a Circular Shaft01:10

Deformation in a Circular Shaft

One of the distinctive characteristics of circular shafts is their ability to maintain their cross-sectional integrity under torsion. In other words, each cross-section continues to exist as a flat, unaltered entity, simply rotating like a solid, rigid slab. To understand the distribution of shearing stress within such a shaft, consider a cylindrical section inside this circular shaft. This section has a length of L and a radius of R, with one end fixed. The radius of the cylindrical section is...
877
Uniform Circular Motion01:14

Uniform Circular Motion

Uniform circular motion is a specific type of motion in which an object travels in a circle with a constant speed. For example, any point on a propeller spinning at a constant rate is undergoing uniform circular motion. The second, minute, and hour hands of a watch also undergo uniform circular motion. It is hard to believe that points on these rotating objects are actually accelerating, even though the rotation rate is constant. To understand this, we must analyze the motion in terms of...
21.6K
Non-uniform Circular Motion01:22

Non-uniform Circular Motion

In uniform circular motion, the particle executing circular motion has a constant speed, and the circle is at a fixed radius. However, not all circular motion occurs at a constant speed. A particle can travel in a circle and speed up or slow down, showing an acceleration in the direction of motion. In that case, the motion is called non-uniform circular motion, and an additional acceleration is introduced, which is in the direction tangential to the circle. 
For example, such...
9.5K
Dynamics of Circular Motion01:30

Dynamics of Circular Motion

An object undergoing circular motion, like a race car, is accelerating because it is changing the direction of its velocity. This centrally directed acceleration is called centripetal acceleration. This acceleration acts along the radius of the curved path (thus is also referred to as radial acceleration).
Any acceleration must be produced by some force. Therefore, any force or combination of forces can cause centripetal acceleration. A few examples include the tension in the rope on a...
23.3K