Related Experiment Video
Updated: Jan 22, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
Published on: April 10, 2018
Procedure coding in the American Joint Replacement Registry.
September R Cahue1, Caryn D Etkin1, Louis S Stryker2
1Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
The Centers for Medicare & Medicaid Services updated to International Classification of Diseases, 10th Edition (ICD-10) in 2015. This transition created challenges for the American Joint Replacement Registry (AJRR) in accurately tracking total joint arthroplasty procedures.
Area of Science:
- Medical Coding and Health Informatics
- Orthopedic Surgery Data Management
Background:
- The Centers for Medicare & Medicaid Services (CMS) mandated a transition from International Classification of Diseases, 9th Edition (ICD-9) to 10th Edition (ICD-10) in October 2015.
- The International Classification of Diseases, 10th Revision, Procedure Coding System (ICD-10-PCS) introduced a significantly larger number of codes, particularly for total joint arthroplasty procedures.
Purpose of the Study:
- To address challenges faced by the American Joint Replacement Registry (AJRR) in accurately identifying specific total joint arthroplasty procedures under the new ICD-10-PCS coding system.
- To improve the precision and reliability of data collected by the AJRR.
Main Methods:
- Formation of an ICD-10 workgroup by the AJRR.
- Definition and mapping of appropriate ICD-10 codes to various total joint procedure types.
- Collaboration between AJRR and participating hospitals/surgeons to navigate the new coding system.
Main Results:
- The AJRR workgroup successfully developed a framework for mapping ICD-10-PCS codes to total joint arthroplasty procedures.
- Enhanced understanding and familiarity with ICD-10-PCS among AJRR stakeholders, including surgeons.
- Improved data accuracy and specificity within the AJRR database.
Conclusions:
- The AJRR's proactive approach in establishing an ICD-10 workgroup effectively mitigated challenges posed by the ICD-10-PCS transition.
- Accurate procedural coding is crucial for the integrity of large joint replacement registries.
- Continued education and clear mapping are essential for successful adoption of new medical coding systems.
Related Concept Videos
lncRNA - Long Non-coding RNAs
lncRNA - Long Non-coding RNAs
Structural Joints: Synovial Joints
Structural Joints: Fibrous Joints
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
Structural Joints: Cartilaginous Joints
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
Joints
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...

