Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Metabolism?00:52

What is Metabolism?

131.3K
Overview
131.3K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.4K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.4K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.2K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.2K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.3K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.3K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.3K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.3K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.1K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of body composition on airway inflammation: analyzing FeNO z-scores in non-asthmatic school-aged children using GAMLSS modeling.

European annals of allergy and clinical immunology·2026
Same author

Correspondence: The First Biosimilar for Biologics in Allergy: CT-P39 (Omlyclo-Omalizumab-Igec) Is Available for Asthma, Chronic Spontaneous Urticaria, and Chronic Rhinosinusitis With Nasal Polyps.

Allergy·2026
Same author

Etiologic diagnosis of seasonal allergic rhinitis supported by artificial intelligence: The @IT-2020 project.

The Journal of allergy and clinical immunology·2026
Same author

Salvage radiotherapy after cryotherapy in prostate cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2026
Same author

The Unmet Need of Olfactory Testing in Inflammatory Disorders of the Upper Airways-An EAACI Position Paper.

Allergy·2026
Same author

Early Detection of Lower Adherence to Long-Term e-Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same journal

Clinical experience with berotralstat in patients with hereditary angioedema: an Italian case series from the ITACA cohort.

European annals of allergy and clinical immunology·2026
Same journal

Multicenter survey on eosinophilic esophagitis in Italy: trends in diagnosis, diagnostic delay, and type 2 comorbidity burden.

European annals of allergy and clinical immunology·2026
Same journal

Art v 3 sensitization is associated with increased immunological complexity but not clinical severity in lipid transfer protein syndrome.

European annals of allergy and clinical immunology·2026
Same journal

Patch test sensitization and permanent tattoos: epidemiological data from two referral centers.

European annals of allergy and clinical immunology·2026
Same journal

Prevalence and clinical outcomes of eosinophilia in critically ill patients.

European annals of allergy and clinical immunology·2026
Same journal

Clinical terminology and biological mediators in allergology: why biomarkers do not define a syndrome.

European annals of allergy and clinical immunology·2026
See all related articles

Related Experiment Video

Updated: Jan 22, 2026

Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

6.5K

Metabolic interactions in asthma.

M Farraia1, J Cavaleiro Rufo1, I Paciência1,2,3

  • 1EPIUnit, Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.

European Annals of Allergy and Clinical Immunology
|July 10, 2019
PubMed
Summary
This summary is machine-generated.

Metabolomics reveals altered metabolic pathways in asthma, offering insights into its pathophysiology. This approach aids in discovering biomarkers and developing targeted treatments for asthma.

Keywords:
asthmametabolic changesmetabolic pathwaysobesity

More Related Videos

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.4K
Asthma Detection Research Based on Voice Signal Processing and Machine Learning
04:04

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

943

Related Experiment Videos

Last Updated: Jan 22, 2026

Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

6.5K
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.4K
Asthma Detection Research Based on Voice Signal Processing and Machine Learning
04:04

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

943

Area of Science:

  • Biochemistry
  • Immunology
  • Pharmacology

Background:

  • Asthma pathophysiology involves complex metabolic alterations.
  • Metabolomics offers a powerful lens to investigate these changes.
  • Understanding metabolic pathways is crucial for effective asthma management.

Purpose of the Study:

  • To review the application of metabolomics in understanding asthma.
  • To describe key metabolic pathways investigated in asthma research.
  • To discuss the clinical implications of metabolomics findings in asthma.

Main Methods:

  • Systematic literature search of PubMed for studies since 2000.
  • Inclusion of studies employing a metabolomics approach.
  • Analysis of 32 selected studies.

Main Results:

  • Identified altered pathways including cellular energy homeostasis, lipid metabolism, oxidative stress, and immune/inflammatory processes.
  • Highlighted the evolution from initial biomarker discovery to evaluating drug effects.
  • Demonstrated potential for identifying pathways for targeted treatments and differentiating asthma phenotypes/severities.

Conclusions:

  • Metabolomics provides valuable insights into asthma pathophysiology.
  • It facilitates biomarker discovery and the development of novel therapeutic strategies.
  • Metabolomics can personalize asthma treatment by considering severity and phenotypes.