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Investigating Cardiac Metabolism in the Isolated Perfused Mouse Heart with Hyperpolarized [1-13C]Pyruvate and 13C/31P NMR Spectroscopy
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Spectroscopy and Two-Photon Dissociation of Jet-Cooled Pyruvic Acid
Subhasish Sutradhar1, Bibek R Samanta1, Ravin Fernando1
1Department of Chemistry , University of Southern California , Los Angeles , California 90089-0482 , United States.
The Journal of Physical Chemistry. A
|July 10, 2019
Summary
UV photodissociation of pyruvic acid (PA) was investigated. This study reveals that PA fragments into multiple products via three-body processes after absorbing additional photons, providing insights into its excited-state dynamics.
Area of Science:
- Photochemistry
- Molecular Spectroscopy
- Chemical Physics
Background:
- Pyruvic acid (PA) is a key molecule in atmospheric chemistry and biological processes.
- Understanding its UV photodissociation is crucial for modeling its environmental fate and reactivity.
Purpose of the Study:
- To investigate the UV photodissociation dynamics of pyruvic acid (PA) in molecular beams.
- To identify photodissociation products and elucidate fragmentation pathways.
Main Methods:
- Time-of-flight (TOF) mass spectroscopy
- Time-sliced velocity map imaging (VMI)
- Photofragment yield (PFY) spectroscopy
Main Results:
- Detected photodissociation products include CH3CO, HOCO, CO, CH3, and H.
- The S1 state of PA has a lifetime longer than a picosecond.
- Three-body fragmentation processes are proposed as the major dissociation pathways.
Conclusions:
- UV excitation of PA leads to complex dissociation dynamics.
- Subsequent photon absorption and rapid dissociation contribute to the observed product distributions.
- The study provides detailed insights into the excited-state behavior and fragmentation of pyruvic acid.
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