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Updated: Jan 22, 2026

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
Published on: July 27, 2022
Non-Resorbable Nanocomposite Membranes for Guided Bone Regeneration Based On Polysulfone-Quartz Fiber Grafted with
Gheorghe Nechifor1, Eugenia Eftimie Totu2, Aurelia Cristina Nechifor3
1Department of Analytical Chemistry and Environment Engineering, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Polizu St., sector 1, 011061 Bucharest, Romania.
Abstract:
The polymer-inorganic nanoparticles composite membranes are the latest solutions for multiple physicochemical resistance and selectivity requirements of membrane processes. This paper presents the production of polysulfone-silica microfiber grafted with titanium dioxide nanoparticles (PSf-SiO2-TiO2) composite membranes. Silica microfiber of length 150-200 μm and diameter 12-15 μm were grafted with titanium dioxide nanoparticles, which aggregated as microspheres of 1-3 μm, applying the sol-gel method. The SiO2 microfibers grafted with nano-TiO2 were used to prepare 12% polysulfone-based nanocomposite membranes in N-methyl pyrrolidone through the inversion phase method by evaporation. The obtained nanocomposite membranes, PSf-SiO2-TiO2, have flux characteristics, retention, mechanical characteristics, and chemical oxidation resistance superior to both the polysulfone integral polymer membranes and the PSf-SiO2 composite membranes. The antimicrobial tests highlighted the inhibitory effect of the PSf-SiO2-TiO2 composite membranes on five Gram (-) microorganisms and did not allow the proliferation of Candida albicans strain, proving that they are suitable for usage in the oral environment. The designed membrane met the required characteristics for application as a functional barrier in guided bone regeneration.
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