Developments in inhibiting platelet aggregation based on different design strategies
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Updated: Jan 22, 2026

Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation
Published on: April 6, 2017
Zhouling Xie1, Yongbin Tian1, Lei Ma1
1School of Food & Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, PR China.
Abstract:
Platelet aggregation is the central event in hemostasis and thrombosis. Up to now, many agents inhibiting platelet aggregation have been approved for the treatment of thrombotic disorders. In this review, we mainly summarized the progress in the research of platelet aggregation inhibitors based on different design strategies. The advantage and challenge of corresponding targets are also discussed in this article. We hope more platelet aggregation inhibitors with efficacy and safety will be discovered in the future.
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