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Related Experiment Video

Updated: Jan 22, 2026

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
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[Fasting - Effects on the Human Body and Psyche].

Rahel Stocker1, Emilie Reber1, Carla Aeberhard1

  • 11 Universitätsklinik für Diabetologie, Endokrinologie, Ernährungsmedizin und Metabolismus, Universitätsspital Bern und Universität Bern.

Praxis
|July 11, 2019
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Summary

Fasting for one week showed varied effects on body and mind in healthy volunteers. This pilot study highlights significant individual differences in responses to fasting.

Keywords:
DiätFastenFastingHungernJeûnerStoffwechseldietfaimmetabolismmétabolismerégimestarvation

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Area of Science:

  • Nutrition Science
  • Human Physiology
  • Psychology

Background:

  • Fasting is increasingly popular for weight loss, well-being, and disease management.
  • The effects of fasting on human health and psychological state are debated.
  • Understanding these effects is crucial given the trend's popularity.

Purpose of the Study:

  • To investigate the physical and psychological effects of a one-week fasting period.
  • To explore potential benefits and drawbacks of fasting in healthy individuals.
  • To document interindividual variations in response to fasting.

Main Methods:

  • A pilot study involving twelve healthy volunteers (10 women, 2 men).
  • Participants underwent a one-week fasting regimen.
  • Clinical parameters (body weight, blood pressure) and mental states (hunger, cold, mood, energy, sleep quality) were monitored.
  • Side effects were systematically recorded.

Main Results:

  • Fasting led to a range of observed effects on both physical and mental parameters.
  • Significant interindividual variations in responses were noted among participants.
  • Specific changes in body weight, blood pressure, mood, and energy levels were documented.

Conclusions:

  • This pilot study demonstrates that one-week fasting elicits diverse effects on the human body and psyche.
  • Remarkable interindividual variability exists in how individuals respond to fasting.
  • Further research is warranted to elucidate the mechanisms and implications of these findings.