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Targeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development

Eric A Wold1, Christopher T Wild1, Kathryn A Cunningham1

  • 1Center for Addiction Research and Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555, United States.

Current Topics in Medicinal Chemistry
|July 11, 2019
PubMed

Keywords:
5-HT2C receptorAgonistsAllosteric modulationCentral nervous system disordersDrug discoveryLigand developmentNeurotherapeuticsPharmacological probesPositive allosteric modulatorsSignaling biasTarget selectivity.

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