Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Granulomatosis polyangiitis.

Mustafa Sowida1

  • 1Birmingham Heartlands Hospital, University Hospital Birmingham, Birmingham, UK.

BMJ Case Reports
|July 11, 2019
PubMed
Summary

A young woman with persistent fevers and weight loss was diagnosed with vasculitis affecting her lungs and pancreas. Prompt treatment with corticosteroids led to significant clinical improvement, highlighting early diagnosis importance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative Glycosylated Haemoglobin (HbA1c) Does Impact on Postoperative Complications in Patients Undergoing Gastrointestinal and Hepatobiliary Surgery.

Asian journal of anesthesiology·2018
Same author

Absence of Association between Preoperative Estimated Glomerular Filtration Rates and Postoperative Outcomes following Elective Gastrointestinal Surgeries: A Prospective Cohort Study.

Anesthesiology research and practice·2018
Same author

Preoperative Assessment of Patients Undergoing Elective Gastrointestinal Surgery: Does Body Mass Index Matter?

Journal of obesity·2017
Same author

Evaluation on preoperative assessment of obese patients.

Journal of clinical anesthesia·2016

Area of Science:

  • Rheumatology
  • Pulmonology
  • Gastroenterology

Background:

  • A 22-year-old female presented with persistent gingivitis and mouth ulcers.
  • She reported a 4-6 week history of fevers, dry cough, and weight loss.

Observation:

  • Imaging revealed bilateral pulmonary nodules and mediastinal lymphadenopathy.
  • Pancreatic lesions were identified as well-defined, non-malignant fluid-filled cysts.
  • Lung biopsies showed vasculitis with granulomata.

Findings:

  • Immunology confirmed c-antinuclear cytoplasmic antibodies and proteinase-3 positivity.
  • The patient's presentation was consistent with a diagnosis of vasculitis.
  • She responded well to corticosteroid therapy, including methylprednisolone and prednisolone.

Implications:

  • This case underscores the importance of considering systemic vasculitis in young adults with unexplained fevers, pulmonary, and pancreatic manifestations.
  • Early diagnosis and treatment with immunosuppressants are crucial for favorable outcomes.
  • Multidisciplinary collaboration between oral medicine, pulmonology, and rheumatology is vital for managing complex cases.
Keywords:
TB and other respiratory infectionspancreas and biliary tractradiologyvasculitis

Related Experiment Videos