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Validation and Normative Data for the Modified Telephone Interview for Cognitive Status: The Sydney Memory and Ageing
Adam C Bentvelzen1, John D Crawford1, Adam Theobald1
1Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.
The modified Telephone Interview for Cognitive Status (TICS-M) effectively screens older adults for dementia. This validated tool offers improved accuracy and accessibility for cognitive assessment in aging populations.
Area of Science:
- Gerontology
- Cognitive Neuroscience
- Psychometrics
Background:
- Telephone-based cognitive screening tools like the Telephone Interview for Cognitive Status (TICS) can reduce barriers to assessing older adults.
- Existing normative data for cognitive screens may lack sensitivity due to inadequate demographic corrections and failure to exclude individuals who later develop dementia.
- Validation in large, comprehensively assessed samples of older adults is needed for clinically relevant psychometric properties.
Purpose of the Study:
- To validate the modified TICS (TICS-M), a 13-item, 39-point version, in a large sample of community-dwelling older adults.
- To provide updated, regression-based normative data that accounts for demographic factors and excludes incident dementia cases.
- To develop an online norms calculator for improved accessibility and cost-effectiveness in cognitive testing.
Main Methods:
- A prospective longitudinal study involving 617 community-living older adults aged 71–91 years.
- Cognitive assessment using the TICS-M, Mini-Mental State Examination (MMSE), Addenbrooke's Cognitive Examination-Revised (ACE-R), and a comprehensive neuropsychological test battery.
- Statistical analyses included descriptive statistics, correlations, area under the curve, and regression analyses to establish validity and normative properties.
Main Results:
- The TICS-M demonstrated good construct validity, correlating well with the MMSE (0.70) and ACE-R (0.80).
- A TICS-M cutoff score of ≤21 reliably distinguished individuals with and without incident dementia after one year (sensitivity 77%, specificity 88%).
- TICS-M scores showed expected demographic relationships, decreasing with age and increasing with education. Normative data from a dementia-excluded sample exhibited higher scores and less variability.
Conclusions:
- The TICS-M exhibits strong construct and diagnostic validity for incident dementia in older adults.
- The provided comprehensive, regression-based normative data enhances the sensitivity, accessibility, and cost-effectiveness of cognitive screening.
- The online norms calculator facilitates practical application of these findings in clinical and research settings.
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