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Biomimetic Materials to Characterize Bacteria-host Interactions
Published on: November 16, 2015
A biomimetic approach towards phorone sesterterpenoids
Harry J Shirley1, Christopher D Bray
1The School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK. c.bray@qmul.ac.uk.
Abstract:
We report an investigation towards a unified total synthesis of the Korean sponge derived sesterterpenoids, phorones A (1) and B (2), via a biomimetic strategy. This work has established a new synthetic strategy to the parent ansellane sesterterpenoid skeleton with unanticipated diversion to a biogenetically related pathway.
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