Related Experiment Video
Updated: Jan 22, 2026

Light-Controlled Fermentations for Microbial Chemical and Protein Production
Published on: March 22, 2022
mSphere of Influence: Systematically Decoding Microbial Chemical Communication
1Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA lmike@umich.edu.
Abstract:
Laura A. Mike works in the field of bacterial pathogenesis. In this mSphere of Influence article, she reflects on how "Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters" by P. Cimermancic et al. (Cell 158:412-421, 2014, https://doi.org/10.1016/j.cell.2014.06.034) and "A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics" by M. S. Donia et al. (Cell 158:1402-1414, 2014, https://doi.org/10.1016/j.cell.2014.08.032) made an impact on her by systematically identifying microbiome-associated biosynthetic gene clusters predicted to synthesize secondary metabolites, which may facilitate interspecies interactions.
Related Concept Videos
Factors Influencing Microbial Growth: pH
Communication
Communication
Factors Influencing Microbial Growth: Temperature
Factors Influencing Microbial Growth: Osmolarity
Chemical Equilibria: Systematic Approach to Equilibrium Calculations
The first step is to identify all the chemical reactions involved, The...

