Pseudotumor Cerebri Syndrome in Children

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Rebecca Barmherzig1,2, Christina L Szperka3,4

  • 1Division of Neurology, Women's College Hospital Centre for Headache, University of Toronto, Toronto, Canada.

Current Pain and Headache Reports
|July 12, 2019
PubMed

Insights

Pseudotumor cerebri syndrome (PTCS) in children presents uniquely, often with subtle signs. Early identification and management are crucial due to risks of vision loss and reduced quality of life.

Area of Science:

  • Pediatric Neurology
  • Ophthalmology
  • Neurology

Background:

  • Pseudotumor cerebri syndrome (PTCS) affects children and adults, but risk factors and presentation differ.
  • Unique considerations for PTCS in pediatric populations require specific attention.

Purpose of the Study:

  • To review the epidemiology, demographics, and clinical presentation of PTCS in children.
  • To discuss revised diagnostic criteria, evaluation, management, and prognosis for pediatric PTCS.
  • To highlight unique aspects of PTCS in the pediatric population.

Main Methods:

  • This is a review article.
  • It synthesizes current knowledge on pediatric PTCS.
  • No specific experimental methods were employed.

Main Results:

  • Clinical presentation of PTCS in children can be subtle and challenging to diagnose.
  • Papilledema diagnosis and upper limits for opening pressure (25 cm H2O, or 28 cm H2O in sedated/obese children) require specific pediatric considerations.
  • Morbidity includes visual loss, pain, and reduced quality of life, underscoring the need for prompt management.

Conclusions:

  • Accurate identification, evaluation, and management of pediatric PTCS are urgent due to potential morbidity.
  • Evidence-based recommendations for PTCS management in children are lacking due to the absence of randomized controlled trials.
  • Further research is needed to establish consolidated management approaches for PTCS in children.
Abstract

Keywords:
AdolescentsChildrenIdiopathic intracranial hypertensionPseudotumor cerebri syndrome

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